Anterior cruciate ligament (ACL) injuries often require a lengthy duration of rehabilitation for patients to return to their prior level of function.Adherence to rehabilitation during this prolonged period can be subpar due to the treatment duration and poor adherence to home exercises.This work evaluates whether a smart instrumented knee brace sys

The past decade has witnessed major breakthroughs in cancer immunotherapy.This development has been largely motivated by cancer cell evasion of immunological control and consequent tumor resistance to conventional therapies.Immunogenic cell death (ICD) is considered one of the most promising ways to achieve total tumor cell elimination.It activates

Abstract Background The origin of the translation system is, arguably, the central and the hardest problem in the study of the origin of life, and one of the hardest in all evolutionary biology.The problem has a clear catch-22 aspect: high translation fidelity hardly can be achieved without a complex, highly evolved set of RNAs and proteins but an

Successful subversion of translation initiation factors eIF4E determines the infection success of potyviruses, the largest group of viruses affecting plants.In the natural variability of many plant species, resistance to potyvirus infection is provided by polymorphisms at eIF4E that renders them inadequate for T-shirts virus hijacking but still fun

We report the case Connecting Wire of a 60-year-old woman with a schwannoma of the medial plantar nerve.She presented with the complaint of pain for about 2 years and a painful lesion in the medial plantar region of the left forefoot and on the second toe.Physical examination showed well-defined, firm tumor masses painful to palpation on the medial